AOD-9604

Product Overview

AOD-9604 (Anti-Obesity Drug Fragment 9604) is a synthetic peptide analog derived from the C-terminal fragment (amino acids 176–191) of the human growth hormone (HGH) molecule. In scientific research, AOD-9604 has been investigated for its lipolytic and anti-lipogenic activity—stimulating the breakdown of stored triglycerides while inhibiting the formation of new fat cells.

These effects occur independently of the growth-promoting actions typically associated with full-length HGH, making AOD-9604 a valuable model for studying non-anabolic growth hormone pathways. Mechanistic studies suggest that AOD-9604 may exert its biological influence through beta-adrenergic receptor modulation and AMP-activated protein kinase (AMPK) signaling, two critical regulators of energy metabolism and fat oxidation.

By enhancing mitochondrial fatty-acid utilization and supporting metabolic homeostasis, AOD-9604 provides researchers with an opportunity to examine molecular mechanisms underlying energy balance, body-composition regulation, and lipid metabolism without affecting insulin sensitivity or IGF-1 levels. Researchers have explored its applications in obesity physiology, metabolic-disorder modeling, and energy-expenditure studies, as well as in investigations assessing post-exercise recovery and metabolic adaptation during caloric restriction.

Because it lacks the anabolic or diabetogenic properties of native HGH, AOD-9604 offers a selective tool for evaluating fat metabolism pathways in isolation. Ongoing research continues to analyze its potential influence on cartilage protection, mitochondrial efficiency, and oxidative stress modulation, further expanding its relevance in the field of metabolic and regenerative peptide science.

Key Research Benefits

• Studied for its ability to stimulate lipolysis and suppress lipogenesis in controlled research environments

• Supports investigations of AMPK signaling, fatty-acid oxidation, and energy-balance regulation

• May aid in understanding non-anabolic mechanisms of fat metabolism distinct from growth hormone receptor activation

• Explored for its effects on obesity models, metabolic-adaptation research, and body-composition optimization

• Demonstrates a favorable stability and safety profile across various preclinical research settings

Disclaimer: All products, including AOD-9604, are sold for laboratory and research purposes only.
Not for human consumption, medical, or veterinary use.